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ManualDetails of Host Protein
| Host Protein General Information (ID: PT0165) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein Name |
Alanyl-tRNA synthetase (AlaRS)
|
Gene Name |
AARS2
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| Host Species |
Homo sapiens
|
Uniprot Entry Name |
SYAM_HUMAN
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| Protein Families |
Class-II aminoacyl-tRNA synthetase family
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| EC Number |
6.1.1.7
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| Subcellular Location |
Mitochondrion
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| External Link | |||||||||
| NCBI Gene ID | |||||||||
| Uniprot ID | |||||||||
| Ensembl ID | |||||||||
| HGNC ID | |||||||||
| Function in Host |
Catalyzes the attachment of alanine to tRNA (Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP andthen transferred to the acceptor end of tRNA (Ala). Also editsincorrectly charged tRNA (Ala) via its editing domain.
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| Related KEGG Pathway | |||||||||
| Aminoacyl-tRNA biosynthesis | hsa00970 |
Pathway Map 
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| 3D Structure |
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| Full List of Virus RNA Interacting with This Protien | |||||||||
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| RNA Region: Not Specified Virus Region (hCoV-19/Not Specified Virus Strain ) | |||||||||
| RNA Region Details |
RNA Info
Click to show the detail information of this RNA binding region
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[1] | |||||||
| Strains Name |
hCoV-19/Not Specified Virus Strain
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| RNA Binding Region |
Not Specified Virus Region
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| Virus Name |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
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| Infection Cells | Huh7 cells (liver carcinoma cell) (CVCL_0336 ) | ||||||||
| Cell Originated Tissue | Liver | ||||||||
| Infection Time | 24h | ||||||||
| Interaction Score | log2FC = 2.69167E+13 | ||||||||
| Method Description | RNA antisense purification and quantitative mass spectrometry (RAP-MS); Tandem mass tag (TMT) labelling; liquid chromatography tandem mass spectrometry (LC-MS/MS); Westernblot | ||||||||
