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ManualDetails of Host Protein
| Host Protein General Information (ID: PT0194) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein Name |
Aspartate--tRNA ligase (DARS)
|
Gene Name |
DARS
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| Host Species |
Homo sapiens
|
Uniprot Entry Name |
Q53T60_HUMAN
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| Protein Families |
Class-II aminoacyl-tRNA synthetase family
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| EC Number |
6.1.1.12
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| External Link | |||||||||
| Uniprot ID | |||||||||
| Ensembl ID | |||||||||
| Function in Host |
Catalyzes the specific attachment of an amino acid to itscognate tRNA in a 2 step reaction: the amino acid (AA) is firstactivated by ATP to form AA-AMP and then transferred to the acceptorend of the tRNA.
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| Full List of Virus RNA Interacting with This Protien | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| RNA Region: ORF10 (hCoV-19/Not Specified Virus Strain ) | |||||||||
| RNA Region Details |
RNA Info
Click to show the detail information of this RNA binding region
|
[1] | |||||||
| Strains Name |
hCoV-19/Not Specified Virus Strain
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| RNA Binding Region |
ORF10
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| Virus Name |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
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| Infection Cells | Huh7 cells (human liver cell line) (CVCL_0336 ) | ||||||||
| Cell Originated Tissue | Liver | ||||||||
| Interaction Score | P-value < 0.05 | ||||||||
| Method Description | RNA pull-down assays; liquid chromatography with tandem mass spectrometry (LC-MS/MS); Wilcoxon test; MS2 affinity purification coupled with liquid chromatography-mass spectrometry (MAMS) | ||||||||
