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ManualDetails of Host Protein
| Host Protein General Information (ID: PT0434) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein Name |
F-actin-capping protein subunit beta (CAPZB)
|
Gene Name |
CAPZB
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| Host Species |
Homo sapiens
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Uniprot Entry Name |
CAPZB_HUMAN
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| Protein Families |
F-actin-capping protein beta subunit family
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| Subcellular Location |
Cytoplasm; cytoskeleton Cytoplasm; myofibril; sarcomere
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| External Link | |||||||||
| NCBI Gene ID | |||||||||
| Uniprot ID | |||||||||
| Ensembl ID | |||||||||
| HGNC ID | |||||||||
| Function in Host |
F-actin-capping proteins bind in a Ca (2+) -independent mannerto the fast growing ends of actin filaments (barbed end) therebyblocking the exchange of subunits at these ends. Unlike other cappingproteins (such as gelsolin and severin), these proteins do not severactin filaments. Plays a role in the regulation of cell morphology andcytoskeletal organization.
[1]
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| Related KEGG Pathway | |||||||||
| Endocytosis | hsa04144 |
Pathway Map 
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| 3D Structure |
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| Full List of Virus RNA Interacting with This Protien | |||||||||
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| RNA Region: Not Specified Virus Region (hCoV-19/USA/WA1/2020 ) | |||||||||
| RNA Region Details |
RNA Info
Click to show the detail information of this RNA binding region
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[2] | |||||||
| Strains Name |
hCoV-19/USA/WA1/2020
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| Strains Family |
Alpha (B.1.1.7)
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| RNA Binding Region |
Not Specified Virus Region
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| Virus Name |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
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| Infection Cells | Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) (CVCL_7927 ) | ||||||||
| Cell Originated Tissue | Liver | ||||||||
| Infection Time | 48 h | ||||||||
| Interaction Score | FDR ≤ 0.05 | ||||||||
| Method Description | comprehensive identification of RNA-binding proteins by massspectrometry (ChIRP-MS) | ||||||||
