Details of Host Protein
Host Protein General Information (ID: PT0696) | |||||||||
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Protein Name |
Nucleolar transcription factor 1 (UBTF)
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Gene Name |
UBTF
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Host Species |
Homo sapiens
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Uniprot Entry Name |
UBF1_HUMAN
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Subcellular Location |
Nucleus; nucleolus
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External Link | |||||||||
NCBI Gene ID | |||||||||
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Ensembl ID | |||||||||
HGNC ID | |||||||||
Function in Host |
Recognizes the ribosomal RNA gene promoter and activatestranscription mediated by RNA polymerase I through cooperativeinteractions with the transcription factor SL1/TIF-IB complex. It bindsspecifically to the upstream control element.
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3D Structure |
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Full List of Virus RNA Interacting with This Protien | |||||||||
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RNA Region: ORF10 (hCoV-19/Not Specified Virus Strain ) | |||||||||
RNA Region Details |
RNA Info
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[1] | |||||||
Strains Name |
hCoV-19/Not Specified Virus Strain
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RNA Binding Region |
ORF10
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Virus Name |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
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Infection Cells | Calu-3 cells (Human Lung Cancer Cell) (CVCL_0609 ) | ||||||||
Cell Originated Tissue | Liver | ||||||||
Interaction Score | P-value < 0.05 | ||||||||
Method Description | RNA pull-down assays; liquid chromatography with tandem mass spectrometry (LC-MS/MS); Wilcoxon test; MS2 affinity purification coupled with liquid chromatography-mass spectrometry (MAMS) |
Differential Gene Expression During SARS-COV-2 Infection | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Protein Phosphorylation after Virus Infection | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S389
[2] |
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S484
[2] |
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S638
[3] |
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S638
[2] |
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T201
[2] |
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Protein Sequence Information |
MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN
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