Details of Host Protein
Host Protein General Information (ID: PT0102) | |||||||||
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Protein Name |
60S ribosomal protein L18 (H3-2)
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Gene Name |
RPL17
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Host Species |
Homo sapiens
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Uniprot Entry Name |
RL17_HUMAN
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Protein Families |
Universal ribosomal protein uL22 family
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External Link | |||||||||
NCBI Gene ID | |||||||||
Uniprot ID | |||||||||
Ensembl ID | |||||||||
HGNC ID | |||||||||
Function in Host |
Component of the large ribosomal subunit.
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Related KEGG Pathway | |||||||||
Coronavirus disease - COVID-19 | hsa05171 |
Pathway Map ![]() |
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Ribosome | hsa03010 |
Pathway Map ![]() |
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3D Structure |
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Host Protein - Virus RNA Network | |||||||||
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Full List of Virus RNA Interacting with This Protien | |||||||||
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RNA Region: 5'-UTR (hCoV-19/South Korea/KCDC03/2020 ) | |||||||||
RNA Region Details |
RNA Info
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[1] | |||||||
Strains Name |
hCoV-19/South Korea/KCDC03/2020
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Strains Family |
Alpha (B.1.1.7)
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RNA Binding Region |
5'-UTR
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Virus Name |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
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Interaction Type | Directly bind to SARS-CoV-23 RNA's 5' UTR region | ||||||||
Infection Cells | Vero cells (epithelial kidney cell) (CVCL_0059 ) | ||||||||
Cell Originated Tissue | kidney | ||||||||
Infection Time | 24 h | ||||||||
Interaction Score | P-adjust < 0.05 | ||||||||
Method Description | Modified RNA antisense purification coupled with mass spectrometry (RAP-MS); label-free quantification (LFQ); liquid chromatography with tandem mass spectrometry (LC-MS/MS) | ||||||||
RNA Region: Not Specified Virus Region (hCov-OC43/VR-759 Quebec/2019 ) | |||||||||
RNA Region Details |
RNA Info
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[1] | |||||||
Strains Name |
hCov-OC43/VR-759 Quebec/2019
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Strains Family |
Beta
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RNA Binding Region |
Not Specified Virus Region
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Virus Name |
Human coronavirus OC43 (HCov-OC43)
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Infection Cells | HCT-8 cells (Human ileocaecal adenocarcinoma cell) HCT-8 cells (Human ileocaecal adenocarcinoma cell) (CVCL_2478 ) | ||||||||
Cell Originated Tissue | Ileocecum | ||||||||
Infection Time | 12h; 24; 36h; 48h | ||||||||
Interaction Score | p_value < 0.05; FDR < 10% | ||||||||
Method Description | Modified RNA antisense purification coupled with mass spectrometry (RAP-MS); label-free quantification (LFQ); liquid chromatography with tandem mass spectrometry (LC-MS/MS) | ||||||||
RNA Region: Not Specified Virus Region (hCoV-19/England/02/2020 ) | |||||||||
RNA Region Details |
RNA Info
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[2] | |||||||
Strains Name |
hCoV-19/England/02/2020
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Strains Family |
Beta (B.1.351)
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RNA Binding Region |
Not Specified Virus Region
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Virus Name |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
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Infection Cells | Calu-3 cells (Human lung cancer cell) Calu-3 cells (Human lung cancer cell) (CVCL_0609 ) | ||||||||
Cell Originated Tissue | Lung | ||||||||
Infection Time | 24 h | ||||||||
Interaction Score | P-adjust = 0.051 | ||||||||
Method Description | UV protein-RNA crosslinking; RNA interactome capture (cRIC); RNA antisense purification coupled with mass spectrometry (RAP-MS) |
Differential Gene Expression During SARS-COV-2 Infection | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Protein Phosphorylation after Virus Infection | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S141
[3] |
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S142
[3] |
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T151
[3] |
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Y139
[3] |
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Protein Sequence Information |
MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE
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