Details of Host Protein

Host Protein General Information (ID: PT0901)
Protein Name	GAP SH3 domain-binding protein 1 (G3BP1)	Gene Name	G3BP1
Host Species	Homo sapiens	Uniprot Entry Name	G3BP1_HUMAN
EC Number	3.6.4.12; 3.6.4.13
Subcellular Location	Cytoplasm; cytosol Perikaryon Cytoplasm; Stress granule Nucleus
External Link
	NCBI Gene ID	10146
	Uniprot ID	Q13283
	Ensembl ID	ENSG00000145907
	HGNC ID	HGNC:30292
Function in Host	ATP- and magnesium-dependent helicase that plays an essentialrole in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding andactivation of CGAS. Enhances also DDX58-induced type I interferonproduction probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stressgranule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bpannealed portion and either a hanging 3' tail or hanging tails at both5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNAsubstrates with comparable efficiency. Actsunidirectionally by moving in the 5' to 3' direction along the boundsingle-stranded DNA. Phosphorylation-dependentsequence-specific endoribonuclease in vitro. Cleavesexclusively between cytosine and adenine and cleaves MYC mRNApreferentially at the 3'-UTR. [1-6] Click to Show/Hide
3D Structure	PDB ID: 3Q90 FASTA Download 2D PNG Download PDB File Download

Function of This Protein During Virus Infection
Virus Name	SARS-COV-2	Protein Function	Pro-viral	[7]
Infected Tissue	Lung	Infection Time	48 h
Infected Cell	Calu-3 cells (Human lung cancer cell line)	Cellosaurus ID	CVCL_0609
Method Description	To detect the role of host protein G3BP1 in viral infection, G3BP1 protein knockout Calu-3 cells were infected with SARS-COV-2 for 48 h , and the effects on infection was detected through qRT-PCR.
Results	It is reported that Knockdown of G3BP1 leads to the reduced SARS-CoV-2 RNA levels compared with control group.

Host Protein - Virus RNA Network

Network Download

Full List of Virus RNA Interacting with This Protien
*RNA Region: 3'-UTR (hCoV-SARS/Manitoba/2003 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-SARS/Manitoba/2003
Strains Family	Beta
RNA Binding Region	3'-UTR
Virus Name	Severe acute respiratory syndrome-related coronavirus (HCoV-SARS)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: 3'-UTR (hCov-OC43/VR-759 Quebec/2019 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCov-OC43/VR-759 Quebec/2019
Strains Family	Beta
RNA Binding Region	3'-UTR
Virus Name	Human coronavirus OC43 (HCov-OC43)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: 3'-UTR (hCov-NL63/Amsterdam/2004 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCov-NL63/Amsterdam/2004
Strains Family	Alpha
RNA Binding Region	3'-UTR
Virus Name	Human Coronavirus NL63 (HCov-NL63)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: 3'-UTR (hCov-MERS/Jeddah/2012 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCov-MERS/Jeddah/2012
Strains Family	Beta
RNA Binding Region	3'-UTR
Virus Name	Middle East respiratory syndrome-related coronavirus (HCov-MERS)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: 3'-UTR (hCoV-HKU1/Hong Kong/2004 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-HKU1/Hong Kong/2004
Strains Family	Beta
RNA Binding Region	3'-UTR
Virus Name	Human coronavirus HKU1 (HCoV-HKU1)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: 3'-UTR (hCov-229E/Würzburg/2000 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCov-229E/Würzburg/2000
Strains Family	Alpha
RNA Binding Region	3'-UTR
Virus Name	Human coronavirus 229E (HCov-229E)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: 3'-UTR (hCoV-19/Wuhan-Hu-1/2019 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Wuhan-Hu-1/2019
Strains Family	Beta (B.1.351)
RNA Binding Region	3'-UTR
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: 5'-UTR (hCoV-19/South Korea/KCDC03/2020 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[7]
Strains Name	hCoV-19/South Korea/KCDC03/2020
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	5'-UTR
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Directly bind to SARS-CoV-23 RNA's 5' UTR region
Infection Cells	Vero cells (epithelial kidney cell) Vero cells (epithelial kidney cell) (CVCL_0059 )
Cell Originated Tissue	kidney
Infection Time	24 h
Interaction Score	P-adjust < 0.05
Method Description	Modified RNA antisense purification coupled with mass spectrometry (RAP-MS); label-free quantification (LFQ); liquid chromatography with tandem mass spectrometry (LC-MS/MS)
*RNA Region: ORF1ab (hCoV-19/Zimbabwe/CERI-KRISP-K034087/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Zimbabwe/CERI-KRISP-K034087/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Wuhan/HBCDC-HB-04/2020 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Wuhan/HBCDC-HB-04/2020
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Venezuela/Bol285/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Venezuela/Bol285/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Switzerland/TI-EOC-902_25839324/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Switzerland/TI-EOC-902_25839324/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Suriname/SR-342/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Suriname/SR-342/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Philippines/PH-PGC-104159/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Philippines/PH-PGC-104159/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Peru/CAL-INS-5458/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Peru/CAL-INS-5458/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Myanmar/DSMRC-065/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Myanmar/DSMRC-065/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Malaysia/MGI_GS0622/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Malaysia/MGI_GS0622/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Ethiopia/ILRI_COVM02835/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Ethiopia/ILRI_COVM02835/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/ElSalvador/INC-LNSP-153/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/ElSalvador/INC-LNSP-153/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Chile/AT-59206/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Chile/AT-59206/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Canada/UN-276648/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Canada/UN-276648/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Bonaire/BQ-RIVM-101067/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bonaire/BQ-RIVM-101067/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Bolivia/CH-INLASA-27102/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bolivia/CH-INLASA-27102/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Bangladesh/CHRF-GSB17-117/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bangladesh/CHRF-GSB17-117/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Australia/SA60463/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Australia/SA60463/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Argentina/PAIS-E0546/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/PAIS-E0546/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Argentina/INEI113521/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI113521/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Argentina/INEI106123/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI106123/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF1ab (hCoV-19/Argentina/INEI104133/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI104133/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF1ab
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Venezuela/Bol285/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Venezuela/Bol285/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Switzerland/TI-EOC-902_25839324/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Switzerland/TI-EOC-902_25839324/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Suriname/SR-342/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Suriname/SR-342/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Peru/CAL-INS-5458/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Peru/CAL-INS-5458/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Bolivia/CH-INLASA-27102/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bolivia/CH-INLASA-27102/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Argentina/PAIS-E0546/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/PAIS-E0546/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Argentina/INEI113521/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI113521/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Argentina/INEI106123/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI106123/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF3a (hCoV-19/Argentina/INEI104133/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI104133/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF3a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF7a (hCoV-19/Namibia/N17380/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Namibia/N17380/2021
Strains Family	Delta (B.1.617.2 and AY lineages)
RNA Binding Region	ORF7a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF7a (hCoV-19/Namibia/CERI-KRISP-K022530/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Namibia/CERI-KRISP-K022530/2021
Strains Family	Delta (B.1.617.2 and AY lineages)
RNA Binding Region	ORF7a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF7a (hCoV-19/Kazakhstan/1872/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Kazakhstan/1872/2021
Strains Family	Delta (B.1.617.2 and AY lineages)
RNA Binding Region	ORF7a
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF8 (hCoV-19/Zambia/ZMB-88673/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Zambia/ZMB-88673/2021
Strains Family	Beta (B.1.351)
RNA Binding Region	ORF8
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF8 (hCoV-19/Venezuela/Bol285/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Venezuela/Bol285/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF8
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF8 (hCoV-19/Malawi/KRISP-K010154/2020 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Malawi/KRISP-K010154/2020
Strains Family	Beta (B.1.351)
RNA Binding Region	ORF8
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF8 (hCoV-19/Eswatini/N2779/2020 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Eswatini/N2779/2020
Strains Family	Beta (B.1.351)
RNA Binding Region	ORF8
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF8 (hCoV-19/Bolivia/CH-INLASA-27102/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bolivia/CH-INLASA-27102/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF8
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF8 (hCoV-19/Argentina/PAIS-E0546/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/PAIS-E0546/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF8
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF8 (hCoV-19/Argentina/INEI113521/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI113521/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF8
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: ORF8 (hCoV-19/Argentina/INEI106123/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI106123/2021
Strains Family	Gamma (P.1)
RNA Binding Region	ORF8
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Zimbabwe/CERI-KRISP-K034087/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Zimbabwe/CERI-KRISP-K034087/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Wuhan/HBCDC-HB-04/2020 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Wuhan/HBCDC-HB-04/2020
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Venezuela/Bol285/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Venezuela/Bol285/2021
Strains Family	Gamma (P.1)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Switzerland/TI-EOC-902_25839324/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Switzerland/TI-EOC-902_25839324/2021
Strains Family	Gamma (P.1)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Suriname/SR-342/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Suriname/SR-342/2021
Strains Family	Gamma (P.1)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Scotland/QEUH-13A999F/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Scotland/QEUH-13A999F/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Scotland/EDB14267/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Scotland/EDB14267/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Philippines/PH-PGC-104159/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Philippines/PH-PGC-104159/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Peru/CAL-INS-5458/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Peru/CAL-INS-5458/2021
Strains Family	Gamma (P.1)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Myanmar/DSMRC-065/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Myanmar/DSMRC-065/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Malaysia/MGI_GS0622/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Malaysia/MGI_GS0622/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Ethiopia/ILRI_COVM02835/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Ethiopia/ILRI_COVM02835/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/England/QEUH-1269F5E/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/England/QEUH-1269F5E/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/England/MILK-F88D46/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/England/MILK-F88D46/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/England/MILK-F88C2B/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/England/MILK-F88C2B/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/England/MILK-1205929/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/England/MILK-1205929/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/England/MILK-11F02FA/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/England/MILK-11F02FA/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/England/LOND-12F444A/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/England/LOND-12F444A/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/England/CAMC-13B6BB7/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/England/CAMC-13B6BB7/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/England/CAMC-12DF946/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/England/CAMC-12DF946/2021
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/ElSalvador/INC-LNSP-153/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/ElSalvador/INC-LNSP-153/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Chile/AT-59206/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Chile/AT-59206/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Canada/UN-276648/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Canada/UN-276648/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Bonaire/BQ-RIVM-101067/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bonaire/BQ-RIVM-101067/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Bangladesh/CHRF-GSB17-117/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bangladesh/CHRF-GSB17-117/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Australia/SA60463/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Australia/SA60463/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Argentina/PAIS-E0546/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/PAIS-E0546/2021
Strains Family	Gamma (P.1)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Argentina/INEI113521/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI113521/2021
Strains Family	Gamma (P.1)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Argentina/INEI106123/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI106123/2021
Strains Family	Gamma (P.1)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: N region (hCoV-19/Argentina/INEI104133/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI104133/2021
Strains Family	Gamma (P.1)
RNA Binding Region	N region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Zimbabwe/CERI-KRISP-K034087/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Zimbabwe/CERI-KRISP-K034087/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Wuhan/HBCDC-HB-04/2020 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Wuhan/HBCDC-HB-04/2020
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Venezuela/Bol285/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Venezuela/Bol285/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Switzerland/TI-EOC-902_25839324/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Switzerland/TI-EOC-902_25839324/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Suriname/SR-342/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Suriname/SR-342/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Philippines/PH-PGC-104159/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Philippines/PH-PGC-104159/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Peru/CAL-INS-5458/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Peru/CAL-INS-5458/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Myanmar/DSMRC-065/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Myanmar/DSMRC-065/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Malaysia/MGI_GS0622/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Malaysia/MGI_GS0622/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Ethiopia/ILRI_COVM02835/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Ethiopia/ILRI_COVM02835/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/ElSalvador/INC-LNSP-153/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/ElSalvador/INC-LNSP-153/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Chile/AT-59206/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Chile/AT-59206/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Canada/UN-276648/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Canada/UN-276648/2021
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Bonaire/BQ-RIVM-101067/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bonaire/BQ-RIVM-101067/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Bolivia/CH-INLASA-27102/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bolivia/CH-INLASA-27102/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Bolivia/CH-INLASA-27102/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bolivia/CH-INLASA-27102/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Bangladesh/CHRF-GSB17-117/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Bangladesh/CHRF-GSB17-117/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Australia/SA60463/2022 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Australia/SA60463/2022
Strains Family	Omicron (B.1.1.529; BA.1; BA.1.1; BA.2; BA.3; BA.4 ; BA.5)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Argentina/PAIS-E0546/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/PAIS-E0546/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Argentina/INEI113521/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI113521/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: S region (hCoV-19/Argentina/INEI104133/2021 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[8]
Strains Name	hCoV-19/Argentina/INEI104133/2021
Strains Family	Gamma (P.1)
RNA Binding Region	S region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Potential binding protein
Infection Cells	HepG2 cells (hepatocellular carcinoma cell line) HepG2 cells (hepatocellular carcinoma cell line) (CVCL_0027 )
Cell Originated Tissue	Liver
Method Description	ENCODE project database; Pysster model; DeepRiPe (Section 3.6; 3.7; 3.8; 3.9); ClustalO (72) algorithm
*RNA Region: Not Specified Virus Region (hCov-OC43/VR-759 Quebec/2019 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[7]
Strains Name	hCov-OC43/VR-759 Quebec/2019
Strains Family	Beta
RNA Binding Region	Not Specified Virus Region
Virus Name	Human coronavirus OC43 (HCov-OC43)
Infection Cells	HCT-8 cells (Human ileocaecal adenocarcinoma cell) HCT-8 cells (Human ileocaecal adenocarcinoma cell) (CVCL_2478 )
Cell Originated Tissue	Ileocecum
Infection Time	12h; 24; 36h; 48h
Interaction Score	p_value < 0.05; FDR < 10%
Method Description	Modified RNA antisense purification coupled with mass spectrometry (RAP-MS); label-free quantification (LFQ); liquid chromatography with tandem mass spectrometry (LC-MS/MS)
*RNA Region: Not Specified Virus Region (hCoV-19/USA/WA1/2020 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[9]
Strains Name	hCoV-19/USA/WA1/2020
Strains Family	Alpha (B.1.1.7)
RNA Binding Region	Not Specified Virus Region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Infection Cells	Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) (CVCL_7927 )
Cell Originated Tissue	Liver
Infection Time	48 h
Interaction Score	FDR ≤ 0.05
Method Description	comprehensive identification of RNA-binding proteins by massspectrometry (ChIRP-MS)
*RNA Region: Not Specified Virus Region (hCoV-19/France/IDF-220-95/2020 )*
RNA Region Details	RNA Info Click to show the detail information of this RNA binding region	[10]
Strains Name	hCoV-19/France/IDF-220-95/2020
RNA Binding Region	Not Specified Virus Region
Virus Name	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Interaction Type	Direct interaction
Infection Cells	HEK293 Cells (Human embryonic kidney cell) HEK293 Cells (Human embryonic kidney cell) (CVCL_0045 )
Cell Originated Tissue	Kidney
Infection Time	48 h
Interaction Score	SAINT score ≥ 0.79
Method Description	comprehensive identification of RNA-binding proteins by massspectrometry (ChIRP-MS)

Differential Gene Expression During SARS-COV-2 Infection

GEO Accession: GSE152641

Sample Type: Blood

Samples Details: Healthy Control: 24; COVID-19: 62

Platform: GPL24676 Illumina NovaSeq 6000

PNG Download

GEO Accession: GSE162835

Sample Type: Nasopharyngeal Swabs

Samples Details: COVID-19 (Mild Symptoms): 37; COVID-19 (Moderate Symptoms): 10; COVID-19 (Severe Symptoms): 3

Platform: GPL24676 Illumina NovaSeq 6000

PNG Download

GEO Accession: GSE175779

Sample Type: Human Bronchial Epithelial Cells

Samples Details: Healthy Control: 4 (0, 24, 48, 72 and 96 h); COVID-19: 4 (24, 48, 72 and 96 h)

Platform: GPL18573 Illumina NextSeq 500

PNG Download

Protein Phosphorylation after Virus Infection
S230 [11] PNG Download
S232 [12] PNG Download
S232 [11] PNG Download
S7 [11] PNG Download
T143 [11] PNG Download

Protein Sequence Information
MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLAPRQ Click to Show/Hide

References
1	G3BP1 promotes DNA binding and activation of cGAS. Nat Immunol. 2019 Jan;20(1):18-28.
2	The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-B response. J Biol Chem. 2019 Apr 19;294(16):6430-6438.
3	Both G3BP1 and G3BP2 contribute to stress granule formation. Genes Cells. 2013 Feb;18(2):135-46.
4	The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation. Biochem J. 2010 Apr 14;427(3):349-57.
5	The RasGAP-associated endoribonuclease G3BP assembles stress granules. J Cell Biol. 2003 Mar 17;160(6):823-31.
6	Human DNA helicase VIII: a DNA and RNA helicase corresponding to the G3BP protein, an element of the ras transduction pathway. Nucleic Acids Res. 1999 Feb 1;27(3):817-21.
7	The SARS-CoV-2 RNA interactome. Mol Cell. 2021 Jul 1;81(13):2838-2850.e6.
8	Computational Mapping of the Human-SARS-CoV-2 Protein-RNA Interactome. bioRxiv. 2021 Dec; DOI:.org/10.1101/2021.12.22.472458.
9	Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions. Cell. 2021 Apr 29;184(9):2394-2411.e16.
10	Characterization and functional interrogation of the SARS-CoV-2 RNA interactome. Cell Rep. 2022 Apr 26;39(4):110744.
11	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Nature. 2021 Jun;594(7862):246-252.
12	The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020 Aug 6;182(3):685-712.e19.

Details of Host Protein

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