Virus RNA General Information
  Strain Information Strain Name
hCoV-19/IPBCAMS-YL01/2020
Strain Family
Beta (B.1.351)
RNA Binding Site
5'-UTR
  Virus Information Virus Name
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Taxonomy ID 2697049

Virus RNA - Host Protein Network
  Regulation Network
  Full list of proteins interacting with the 5'-UTR of this Strain
           hnRNP A1 messenger RNA (HNRNPA1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.932
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           IGF2-binding protein 1 (IMP-1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.983
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Polypyrimidine tract-binding protein (PTBP1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.899
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Heterogeneous nuclear ribonucleoprotein K (HNRNPK)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.928
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           NonO protein (NONO)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.87
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Cleavage stimulation factor 64 kDa subunit (CstF-64)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.973
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           E1B-55 kDa-associated protein 5 (E1B-AP5)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.95
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           EBNA2 coactivator p100 (SND1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.963
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Far upstream element-binding protein 2 (KHSRP)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.98
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           GAP-associated tyrosine phosphoprotein p62 (KHDRBS1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.862
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           General transcription factor IIF subunit 1 (GTF2F1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.95
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Helicase MOV-10 (MOV10)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.92
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Heterogeneous nuclear ribonucleoprotein F (HNRNPF)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.945
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Histone-glutamine methyltransferase (FBL)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.941
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           IGF2-binding protein 2 (IMP-2)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.894
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           IGF2-binding protein 3 (IMP-3)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.941
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Interleukin enhancer-binding factor 3 (ILF3)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.902
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Nucleolar protein 56 (NOP56)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.954
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Nucleolysin TIAR (TIAL1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.947
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Nucleophosmin (NPM1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.93
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Oxidative stress-associated Src activator (OSSA)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.891
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Pre-mRNA-splicing factor RBM22 (RBM22)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.959
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Protein quaking (QKI)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.859
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Regulator of nonsense transcripts 1 (NORF1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.982
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Ribosome maturation protein SBDS (SBDS)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.94
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           RNA helicase-related protein (RNAHP)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.864
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           RNA-binding protein 27 (RBM27)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.924
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           Splicing factor U2AF 65 kDa subunit (U2AF2)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.882
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           T-cell-restricted intracellular antigen-1 (TIA-1)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.935
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           TROVE domain family member 2 (TROVE2)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.979
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry
           WD repeat-containing protein 33 (WDR33)
              Protein Details Pro Info Click to show the detail information of this Protein [1]
              Infection Time 30 h
              Infection Cells Huh7.5.1 cells (Hepatocyte derived cellular carcinoma cell)  (CVCL_E049 )
              Cell Originated Tissue Liver
              Interaction Score Affinity = 0.983
              Description of Detection Method PrismNet; pull-down western (STAR methods); Mass spectrometry

References
1 In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs. Cell. 2021 Apr 1;184(7):1865-1883.e20.